Joel M Reid Selected Research

4-hydroxy-N-desmethyltamoxifen

1/2022	Population Pharmacokinetics of Z-Endoxifen in Patients With Advanced Solid Tumors.
12/2021	Endoxifen, an Estrogen Receptor Targeted Therapy: From Bench to Bedside.
2/2021	Phase 1 study of Z-endoxifen in patients with advanced gynecologic, desmoid, and hormone receptor-positive solid tumors.
1/2020	Antitumor activity of Z-endoxifen in aromatase inhibitor-sensitive and aromatase inhibitor-resistant estrogen receptor-positive breast cancer.
10/2017	First-in-Human Phase I Study of the Tamoxifen Metabolite Z-Endoxifen in Women With Endocrine-Refractory Metastatic Breast Cancer.
10/2017	Skeletal and Uterotrophic Effects of Endoxifen in Female Rats.
4/2015	Evaluation of CYP2D6 enzyme activity using a 13C-dextromethorphan breath test in women receiving adjuvant tamoxifen.
12/2014	Comparative uterotrophic effects of endoxifen and tamoxifen in ovariectomized Sprague-Dawley rats.
12/2014	Pharmacokinetics of endoxifen and tamoxifen in female mice: implications for comparative in vivo activity studies.

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Joel M Reid Research Topics

Disease

86	Neoplasms (Cancer) 10/2022 - 02/2002
11	Breast Neoplasms (Breast Cancer) 12/2021 - 12/2008
11	Neutropenia 01/2021 - 02/2002
9	Thrombocytopenia (Thrombopenia) 01/2021 - 09/2005
8	Glioma (Gliomas) 10/2022 - 05/2003
7	Neuroblastoma 12/2020 - 07/2006
7	Leukemia 01/2019 - 09/2005
6	Nausea 12/2020 - 06/2005
5	Vomiting 12/2020 - 06/2005
5	Fatigue 01/2018 - 06/2005
5	Diarrhea 01/2018 - 06/2005
4	Lymphoma (Lymphomas) 10/2022 - 09/2011
4	Melanoma (Melanoma, Malignant) 01/2020 - 02/2004
4	Central Nervous System Neoplasms 01/2020 - 03/2007
3	Dehydration (Water Stress) 01/2020 - 08/2005
3	Ewing Sarcoma (Sarcoma, Ewing) 01/2020 - 01/2012
3	Hypertension (High Blood Pressure) 12/2018 - 10/2008
3	Pain (Aches) 01/2018 - 01/2016
3	Glioblastoma (Glioblastoma Multiforme) 05/2016 - 04/2009
3	Anorexia 03/2013 - 04/2010
2	Aggressive Fibromatosis (Desmoid) 12/2021 - 02/2021
2	Peripheral Nervous System Diseases (PNS Diseases) 12/2021 - 04/2008
2	Lymphopenia (Lymphocytopenia) 01/2021 - 09/2013
2	Anemia 01/2021 - 09/2013
2	Low Back Pain (Lumbago) 01/2018 - 01/2016
2	Mucositis 01/2018 - 09/2005
2	Proteinuria 01/2018 - 08/2013
2	Endometrial Neoplasms (Endometrial Cancer) 10/2017 - 12/2014
2	Hemorrhagic Cystitis 06/2016 - 06/2015
2	Hematologic Neoplasms (Hematological Malignancy) 01/2016 - 07/2015
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 07/2015 - 08/2008
2	Exanthema (Rash) 07/2014 - 06/2005
2	Sarcoma (Soft Tissue Sarcoma) 08/2013 - 04/2010
2	Body Weight (Weight, Body) 04/2013 - 01/2008

Drug/Important Bio-Agent (IBA)

10	Vorinostat FDA Link 01/2018 - 04/2009
9	4-hydroxy-N-desmethyltamoxifenIBA 01/2022 - 12/2014
9	Irinotecan (Camptosar)FDA LinkGeneric 01/2020 - 05/2003
8	Tamoxifen FDA LinkGeneric 12/2021 - 12/2014
8	Temozolomide (Temodar)FDA LinkGeneric 01/2020 - 05/2003
7	Pharmaceutical PreparationsIBA 01/2021 - 12/2008
7	Gemcitabine FDA Link 01/2013 - 01/2003
7	Carboplatin (JM8)FDA LinkGeneric 02/2007 - 08/2002
6	Estrogen ReceptorsIBA 12/2021 - 03/2015
6	EnzymesIBA 10/2019 - 10/2005
5	Topotecan (Hycamtin)FDA LinkGeneric 01/2018 - 02/2002
4	Transaminases (Aminotransferases)IBA 01/2018 - 06/2005
4	SteroidsIBA 01/2018 - 04/2009
4	Bortezomib (Velcade)FDA Link 04/2014 - 02/2007
4	alvocidib (flavopiridol)IBA 04/2013 - 08/2005
4	Proteins (Proteins, Gene)FDA Link 11/2011 - 07/2003
3	Alanine Transaminase (SGPT)IBA 12/2020 - 04/2015
3	Bevacizumab (Avastin)FDA Link 01/2020 - 01/2008
3	Monoclonal AntibodiesIBA 01/2020 - 08/2008
3	MLN 8237IBA 01/2019 - 04/2016
3	Lipase (Acid Lipase)FDA Link 12/2018 - 08/2013
3	veliparibIBA 01/2018 - 09/2011
3	Triamcinolone Acetonide (Azmacort)FDA LinkGeneric 01/2018 - 01/2016
3	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 10/2017 - 12/2014
3	DNA (Deoxyribonucleic Acid)IBA 10/2017 - 07/2002
3	Anticonvulsants (Antiepileptic Drugs)IBA 11/2015 - 10/2005
3	Antineoplastic Agents (Antineoplastics)IBA 06/2015 - 07/2002
3	Biological ProductsIBA 04/2015 - 01/2008
3	cixutumumabIBA 04/2015 - 01/2012
3	tanespimycin (17AAG)IBA 11/2011 - 03/2007
3	Paclitaxel (Taxol)FDA LinkGeneric 04/2008 - 03/2005
3	Pemetrexed (MTA)FDA Link 04/2007 - 06/2005
3	NSC 366140 (pyrazoloacridine)IBA 10/2005 - 08/2002
3	Cisplatin (Platino)FDA LinkGeneric 08/2005 - 02/2002
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 10/2022 - 01/2022
2	AZD 6244IBA 10/2022 - 01/2022
2	Cystatin CIBA 01/2022 - 01/2019
2	adavosertibIBA 01/2022 - 01/2020
2	Phosphotransferases (Kinase)IBA 01/2022 - 12/2018
2	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2022 - 12/2018
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 01/2016
2	Hormones (Hormone)IBA 12/2021 - 02/2021
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 05/2016
2	Vincristine (Oncovin)FDA LinkGeneric 01/2021 - 04/2010
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 12/2020 - 04/2008
2	Aromatase InhibitorsIBA 01/2020 - 01/2019
2	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 10/2019 - 07/2002
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2018 - 10/2010
2	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2018 - 09/2011
2	BilirubinIBA 01/2018 - 07/2006
2	Immunoglobulin G (IgG)IBA 01/2018 - 01/2016
2	batracylinIBA 06/2016 - 06/2015
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 04/2016 - 02/2002
2	CreatinineIBA 10/2015 - 04/2013
2	epratuzumabIBA 07/2015 - 08/2008
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 06/2015 - 10/2010
2	temsirolimus FDA Link 04/2015 - 10/2012
2	Alkaline PhosphataseIBA 07/2014 - 07/2006
2	Histone Deacetylase InhibitorsIBA 09/2013 - 04/2009
2	Cetuximab (Erbitux)FDA Link 01/2013 - 03/2008

Therapy/Procedure

17	Therapeutics 10/2022 - 05/2003
8	Drug Therapy (Chemotherapy) 12/2020 - 06/2003
4	Radiotherapy 11/2012 - 05/2003
3	Injections 01/2018 - 01/2016
2	Oral Administration 06/2015 - 01/2008
2	Chemoprevention 04/2013 - 03/2008